MIRACLE doctoral candidates (DCs) will be trained to obtain a unique combination of skills in innovative high-tech technologies, advanced data analysis tools and artificial intelligence, organ-on-chip MRD models, as well as drug and immunotherapy testing. Our DCs are encouraged to come up with innovative ideas to advance future leukemia treatment by integration of several disciplines and data sources. Our joint programme consists of an individual research project and a comprehensive training program including international mobility and intersectoral secondments.
Doctoral Candidates
Mai Huong Pham
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Host organisation: Amsterdam UMC, Netherlands
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Supervisors: Prof. Jacqueline Cloos and Dr. Costa Bachas
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Research project: DC1 - Optimizing treatment decisions by using MRD data combined with artificial intelligence >
Alyssa Rodrigues Alvaro
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Host organisation: Charles University, Prague, Czech Republic
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Supervisors: Prof.dr. Prof. Jan Trka and Dr. Jan Stuchly
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Research project: DC2 - In-depth analysis of phenotypic acute leukemia MRD dynamics using single-cell data and advanced computational techniques >
Nurbanu Erölmez
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Host organisation: MIMETAS, Leiden, The Netherlands
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Supervisors: Dr. Karla Queiroz
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Research project: DC3 - The Establishment of Clinical Translational AML MRD On-Chip Models >
Alessandro Gagliardi
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Host organisation: Amsterdam UMC, Amsterdam, The Netherlands
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Supervisors: Dr. Linda Smit and Dr. Rachel Thijssen
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Research project: DC04- Characterization of AML MRD using single cell transcriptomic and epigenetic analysis >
Arif Kocak
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Host organisation: VIB-KU Leuven Center for Cancer Biology, Leuven, Belgium.
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Supervisors: Prof.Dr. Jan Cools
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Research project: DC5 - The characterization of acute lymphoblastic leukemia MRD and relapse using single cell omics >
Nishika Gupta
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Host organisation: INSERM, Institut de la leucémie Paris Saint-Louis, France
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Supervisors: Prof. Dr. Raphael Itzykson and Dr. Matthieu Duchmann
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Research project: DC6 - Multiomic and Metabolomic Characterization of AML Residual Disease after AZA/VEN Treatment >
Thomas Henderson
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Host organisation: Universidad de Sevilla, Seville, Spain
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Supervisors: Prof. Simón Méndez-Ferrer
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Research project: DC07 - Dissecting and targeting niche-dependent vulnerabilities of protection from therapy in AML >
Maria Rodrigues Lopes
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Host organisation: Ospedale San Raffaele, Milan, Italy
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Supervisors: Prof.dr. Raffaella Di Micco and Dr.Antonella Santoro
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Research project: DC8 - Therapy-induced senescence as anti-cancer and immune-stimulatory strategy in AML >
Matija Kovic
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Host organisation: Goethe-Universität Frankfurt, Frankfurt am Main, Germany
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Supervisors: Prof.dr. Jan-Henning Klusmann
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Research project: DC9 - Characterization of persisting leukemic blasts in Down syndrome patients to define targets for immunotherapy >
Pierluigi Carulli
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Host organisation: Ludwig-Maximilians-Universität (LMU) München, Germany
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Supervisors: Prof.dr. Marion Subklewe
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Research project: DC10 - Targeting MRD and LSCs in the bone marrow niche by chemokine modified, dual targeting CAR T cells in AML >